KPV
$900.00
KPV is an anti-inflammatory tripeptide studied for its ability to reduce cell signaling pathways linked to swelling and tissue injury. Because it does not affect skin pigmentation, it is a primary subject for research into gut inflammation, wound healing, and antimicrobial mechanisms.
Research Use Only
This product is a synthesized reagent intended for laboratory research and in vitro studies only. It is not for human consumption, veterinary use, or therapeutic application.
KPV is a C-terminal tripeptide fragment of $\alpha$-MSH. In biochemical research, it is studied for its ability to modulate the NF-$\kappa$B signaling pathway, which is a primary driver of the inflammatory response. Unlike the full $\alpha$-MSH molecule, KPV does not bind to melanocortin receptors involved in pigmentation (MC1R), making it a selective subject for investigating cytokine suppression, antimicrobial activity, and wound healing mechanisms in non-pigmented tissues.
- CAS Number: 67727-97-3
- Molecular Formula: $C_{16}H_{30}N_{4}O_{4}$
- Molecular Weight: 342.4 g/mol
- Amino Acid Sequence: Lys-Pro-Val
- Purity: $\ge$99% (Verified by HPLC & MS)
- Physical Appearance: White Lyophilized Powder
In practical research, KPV is often explored as a "natural antibiotic" and anti-inflammatory agent. Researchers focus on this peptide for its potential to soothe gut inflammation (such as in models of IBD) and accelerate skin repair for conditions like psoriasis or eczema. Because of its small molecular size, it is a key subject for studies involving transdermal delivery and targeted cellular repair, offering a specialized way to study inflammation reduction without affecting the rest of the hormonal system.
We maintain an Analytical Grade standard of $\ge$99% for all KPV batches. Each 10mg vial is vacuum-sealed and undergoes rigorous High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure the precise chemical identity required for consistent immunological data.
- Current Lot: SCP-KPV-10MG-714
- [View Certificate of Analysis (PDF)]
- Solubility: Freely soluble in bacteriostatic water or 0.9% sterile saline.
- Storage: Store lyophilized powder at -20°C for long-term stability.
- Post-Reconstitution: Once reconstituted, the solution should be stored at 2-8°C (36-46°F). For experimental integrity, it is recommended to utilize the solution within 21–30 days.
MAECENAS IACULIS
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