Retatrutide
$900.00
Retatrutide (LY3437943) is an advanced metabolic research peptide known as a “Triple Agonist” because it targets three distinct energy pathways: GLP-1, GIP, and glucagon receptors. This premium 5mg compound is highly sought after for studying weight management, cellular fat metabolism, and energy regulation.
Research Use Only
This product is a synthesized reagent intended for laboratory research and in vitro studies only. It is not for human consumption, veterinary use, or therapeutic application.
Retatrutide (developmental code LY3437943) is an engineered, lipidated 39-amino-acid modified peptide. In biochemical and metabolic research, it functions as a single-molecule triple hormone receptor agonist, demonstrating binding affinities for the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon (GCG) receptors. Researchers study this compound to analyze the compound's downstream impact on pancreatic beta-cell insulin secretion, gastric emptying delays, and the multi-pathway regulation of energy homeostasis within the cellular matrix.
- CAS Number: 2381089-83-2
- Molecular Formula: $C_{221}H_{342}N_{46}O_{68}$
- Molecular Weight: 4731.34 g/mol
- Amino Acid Sequence: H-Tyr-(Aib)-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-(α-Me-Leu)-Leu-Asp-Lys-(diacid-C20-gamma-Glu-(AEEA)-Lys)-Ala-Gln-(Aib)-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-$NH_2$
- Purity: $\ge$99% (Verified by HPLC & MS)
- Physical Appearance: Fine White Lyophilized Powder
In ongoing laboratory models, Retatrutide is often referred to as the "Triple G" or "Triple Agonist" peptide due to its unique unimolecular polypharmacology. Experimental focus centers heavily on its distinct capacity to recruit the glucagon receptor alongside standard incretin pathways, allowing researchers to observe changes in lipolysis, metabolic expenditure, and hepatic fat reduction. Its structural modifications, including a C20 fatty acid diacid moiety, are deeply investigated for their role in prolonging half-life and stabilizing pharmacokinetics in in vitro environments.
We maintain a strict Analytical Grade standard of $\ge$99% for all Retatrutide batches. Each 5mg vial is vacuum-sealed and undergoes rigorous High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm structural identity and sequence integrity required for high-fidelity metabolic profiling.
- Current Lot: SCP-RETA-5MG-904
- [View Certificate of Analysis (PDF)]
- Solubility: Soluble in water or 0.9% sterile saline (recommended concentration up to 5mg/mL).
- Storage: Store un-reconstituted, lyophilized powder at -20°C for long-term stability and protection from degradation.
Post-Reconstitution: Once reconstituted, the solution must be stored at 2-8°C (36-46°F) and protected from light exposure. For experimental integrity and to avoid peptide hydrolysis, it is recommended to utilize the solution within 30 days.
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